--- title: "The Hol Picture: Our Insights on RWE and Behavioral Health | behavioral health" description: behavioral health | Sharing insights to enhance research and care and improve behavioral health conditions for all --- [![](https://info.holmusk.com/hs-fs/hubfs/Holmusk_masterlogo_blue-1.png?width=770&height=263&name=Holmusk_masterlogo_blue-1.png)](https://www.holmusk.com/) Open main menu Close main menu # The Hol Picture Our Insights on Real-World Evidence and Behavioral Health - [ABOUT US](https://www.holmusk.com/about-us/vision) - [JOIN US](https://www.holmusk.com/careers) Posts about: ## behavioral health ![A team of colleagues working on oversized gears](https://info.holmusk.com/hubfs/data%20density_blog%204.png) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [RWD,](https://info.holmusk.com/blog/tag/rwd) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [clinical research,](https://info.holmusk.com/blog/tag/clinical-research) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [NLP,](https://info.holmusk.com/blog/tag/nlp) [natural language processing,](https://info.holmusk.com/blog/tag/natural-language-processing) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [clinical data,](https://info.holmusk.com/blog/tag/clinical-data) [data density](https://info.holmusk.com/blog/tag/data-density) ### [NeuroBlu NLP: A Technical Deep Dive into Developing NLP models for Clinical Insights](https://info.holmusk.com/blog/neuroblu-nlp-a-technical-deep-dive-into-developing-nlp-models-for-clinical-insights) Feb 14, 2024 1:44:52 PM The landscape of mental health research is evolving, and tools like Natural Language Processing (NLP) hold immense potential to bridge the gap between clinical trials and real-world evidence. As we strive to enhance our understanding of mental health outcomes and treatment effectiveness, a strategic implementation of NLP tools becomes pivotal. This blog explores a high-level overview of how we developed NeuroBlu NLP - Holmusk’s NLP models specifically tailored for extracting disease-specific clinical features from unstructured clinical text. These NLP-derived clinical features are then integrated into our structured data and made available in NeuroBlu, Holmusk’s powerful data analytics software for behavioral health. The incorporation of NLP-derived features into structured data provides a more comprehensive, easily accessible estimate of patient phenotypes in the real-world, ultimately benefiting patient care. ![Deepali Kulkarni](https://info.holmusk.com/hs-fs/hubfs/Deepali_Kulkarni_pic.jpg?width=45&name=Deepali_Kulkarni_pic.jpg) [Deepali Kulkarni](https://info.holmusk.com/blog/author/deepali-kulkarni) [Read More](https://info.holmusk.com/blog/neuroblu-nlp-a-technical-deep-dive-into-developing-nlp-models-for-clinical-insights) ![A team of researchers at a computer, viewing charts and graphs](https://info.holmusk.com/hubfs/data%20density_blog%203%20(1).png) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [RWD,](https://info.holmusk.com/blog/tag/rwd) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [clinical research,](https://info.holmusk.com/blog/tag/clinical-research) [natural language processing,](https://info.holmusk.com/blog/tag/natural-language-processing) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [clinical data,](https://info.holmusk.com/blog/tag/clinical-data) [data density](https://info.holmusk.com/blog/tag/data-density) ### [How NLP-enriched data advances clinical research](https://info.holmusk.com/blog/how-nlp-enriched-data-advances-clinical-research) Oct 4, 2023 12:26:52 PM Real-world evidence has been increasingly recognized as an important complement to clinical research. In clinical research, randomized controlled trials often have stringent inclusion criteria which may exclude certain patient groups, such as those with comorbidities. When clinical trial populations diverge from patient populations seen in a real-world care setting, insights gained might not be widely applicable to all people. Analyzing real-world data, such as clinical information recorded in electronic health records (EHR) as part of routine clinical care, can provide insights that are generalizable to real-world populations. ![Kira Griffiths](https://info.holmusk.com/hs-fs/hubfs/KG_Headshot.jpeg?width=45&name=KG_Headshot.jpeg) [Kira Griffiths](https://info.holmusk.com/blog/author/kira-griffiths) [Read More](https://info.holmusk.com/blog/how-nlp-enriched-data-advances-clinical-research) ![A man standing before a winding path embedded with symbols in a forest with mountains in the background.](https://info.holmusk.com/hubfs/data%20density%20blog%202%20(1).png) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [RWD,](https://info.holmusk.com/blog/tag/rwd) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [clinical data,](https://info.holmusk.com/blog/tag/clinical-data) [data density](https://info.holmusk.com/blog/tag/data-density) ### [Enhancing Data Density in EHR Data for Behavioral and Mental Health Analysis: The 4 I's Approach](https://info.holmusk.com/blog/ehr-data-claims-data-and-what-each-can-offer-for-behavioral-health-research-0) Sep 20, 2023 10:00:00 AM In the realm of behavioral and mental health, electronic health records (EHR) data is a goldmine of information. However, the challenge lies in the fact that these data often need more density for comprehensive analysis. ![Kevin Holland](https://info.holmusk.com/hs-fs/hubfs/Kevin%20headshot.jpeg?width=45&name=Kevin%20headshot.jpeg) [Kevin Holland](https://info.holmusk.com/blog/author/kevin-holland) [Read More](https://info.holmusk.com/blog/ehr-data-claims-data-and-what-each-can-offer-for-behavioral-health-research-0) ![a series of question marks and ideas represented as light bulbs](https://info.holmusk.com/hubfs/question-g648e864e1_1920.jpg) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [RWD,](https://info.holmusk.com/blog/tag/rwd) [outcomes,](https://info.holmusk.com/blog/tag/outcomes) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [healthcare,](https://info.holmusk.com/blog/tag/healthcare) [EHR,](https://info.holmusk.com/blog/tag/ehr) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [clinical data](https://info.holmusk.com/blog/tag/clinical-data) ### [What questions can EHR data answer for biopharmaceutical teams?](https://info.holmusk.com/blog/what-questions-can-ehr-data-answer-for-biopharmaceutical-teams) Aug 2, 2023 8:46:54 AM The treatment of behavioral health conditions has historically been challenging. Despite the prevalent use of the DSM-V in clinical settings, clinicians lack a detailed and standardized vocabulary to discuss these conditions. This is due to a range of factors, from wide differences in disease presentation to stigma surrounding mental health conditions. The lack of standardized vocabulary has led to a subjective approach in treating these conditions, with each clinician relying on his or her own experience. However, as more and more patients who are treated for behavioral health conditions are documented within an electronic health record (EHR) system, researchers now have a valuable tool for studying and improving the treatment of behavioral health conditions. By bringing together vast quantities of real-world data to understand how care and treatment are delivered in clinical practice, we can start building a set of standard definitions and objective measures for mental health conditions. This is why we have created the [NeuroBlu Database](https://www.neuroblu.ai/), in which we have extracted and organized EHR data from behavioral health clinics across the U.S. Our NeuroBlu data has thus far been leveraged by 5 of the top 15 biopharmaceutical companies with a behavioral health pipeline. These companies can benefit greatly from EHR-derived real-world data, particularly in the areas of research and development, medical affairs, and health economics and outcomes research (HEOR). ![Karthik Chandran](https://info.holmusk.com/hs-fs/hubfs/Bio%20Picture%20(1).jpg?width=45&name=Bio%20Picture%20(1).jpg) [Karthik Chandran](https://info.holmusk.com/blog/author/karthik-chandran) [Read More](https://info.holmusk.com/blog/what-questions-can-ehr-data-answer-for-biopharmaceutical-teams) ![](https://info.holmusk.com/hubfs/rc-xyz-nft-gallery--o90yRQoXAM-unsplash.jpg) [RWD,](https://info.holmusk.com/blog/tag/rwd) [outcomes,](https://info.holmusk.com/blog/tag/outcomes) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [data capture,](https://info.holmusk.com/blog/tag/data-capture) [claims data,](https://info.holmusk.com/blog/tag/claims-data) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [clinical data](https://info.holmusk.com/blog/tag/clinical-data) ### [EHR Data Hold the Key to Improving and Accelerating Behavioral Health Research](https://info.holmusk.com/blog/ehr-data-hold-the-key-to-improving-and-accelerating-behavioral-health-research) Jul 6, 2023 9:43:22 AM *This is an excerpt from a longer post that originally appeared on* [Going Digital: Behavioral Health Tech](https://www.behavioralhealthtech.com/insights/ehr-data-hold-the-key-to-improving-and-accelerating-behavioral-health-research). Real-world data (RWD) are becoming increasingly critical to clinical research. The FDA has put forth [definitions surrounding RWD](https://www.fda.gov/science-research/science-and-research-special-topics/real-world-evidence), as well as issued guidance around its use in research emphasizing the principle of data being “fit-for-purpose”—selecting the data needed to answer the question at hand. Meanwhile, stakeholders engaged in clinical development have increasingly recognized that RWD will enable them to conduct studies faster, at a lower cost, and often, with a more representative and diverse population. However, not all RWD is fit-for-purpose—that is, captured and stored in such a way that the data is ready to address the question at hand. In order to move forward with using RWD in a way that is efficient and effective, we need to build a shared understanding of the different types of data within the broad umbrella that is RWD and make clear which type of RWD is fit-for-purpose for a specific question. ![Alex Vance](https://info.holmusk.com/hs-fs/hubfs/Alex%20Vance.jpeg?width=45&name=Alex%20Vance.jpeg) [Alex Vance](https://info.holmusk.com/blog/author/alex-vance) [Read More](https://info.holmusk.com/blog/ehr-data-hold-the-key-to-improving-and-accelerating-behavioral-health-research) ![](https://info.holmusk.com/hubfs/June%202023%20(3).png) [mental health,](https://info.holmusk.com/blog/tag/mental-health) [outcomes,](https://info.holmusk.com/blog/tag/outcomes) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [healthcare,](https://info.holmusk.com/blog/tag/healthcare) [public health,](https://info.holmusk.com/blog/tag/public-health) [innovation,](https://info.holmusk.com/blog/tag/innovation) [data science,](https://info.holmusk.com/blog/tag/data-science) [data analytics](https://info.holmusk.com/blog/tag/data-analytics) ### [Exciting government-supported collaboration will drive improved mental health in the U.K.](https://info.holmusk.com/blog/exciting-government-supported-collaboration-will-drive-improved-mental-health-in-the-u.k) Jun 5, 2023 7:30:00 PM The HM Treasury in the United Kingdom recently announced an exciting and truly forward-looking initiative for healthcare: a package of government funding, called the [Life Sci for Growth](https://www.gov.uk/government/news/chancellor-reveals-life-sciences-growth-package-to-fire-up-economy) package, to fuel research and bring treatments to patients faster. There are many impressive projects being funded, from clinical trial improvements to preparation efforts for future public health emergencies.  ![Nawal Roy](https://info.holmusk.com/hs-fs/hubfs/BD-Nawal%20Roy.png?width=45&name=BD-Nawal%20Roy.png) [Nawal Roy](https://info.holmusk.com/blog/author/nawal-roy) [Read More](https://info.holmusk.com/blog/exciting-government-supported-collaboration-will-drive-improved-mental-health-in-the-u.k) ![](https://info.holmusk.com/hubfs/Mental%20Health%20Month%202023%20(1).png) [mental health,](https://info.holmusk.com/blog/tag/mental-health) [RWD,](https://info.holmusk.com/blog/tag/rwd) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [suicide prevention,](https://info.holmusk.com/blog/tag/suicide-prevention) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [NLP,](https://info.holmusk.com/blog/tag/nlp) [natural language processing,](https://info.holmusk.com/blog/tag/natural-language-processing) [socioenvironmental factors](https://info.holmusk.com/blog/tag/socioenvironmental-factors) ### [Capitalizing on untapped value: Extracting environmental stressors from clinical notes via natural language processing](https://info.holmusk.com/blog/capitalizing-on-untapped-value-extracting-environmental-stressors-from-clinical-notes-via-natural-language-processing) May 22, 2023 7:30:00 AM Consider an emergency room doctor who is caring for a patient who has been hospitalized after a suicide attempt. When she consults his chart, she can see that he has been diagnosed with depression, but the structured data that is immediately available does not provide much additional context.  ![Abhijit Ghosh](https://info.holmusk.com/hs-fs/hubfs/abhijit.jpeg?width=45&name=abhijit.jpeg) [Abhijit Ghosh](https://info.holmusk.com/blog/author/abhijit-ghosh) [Read More](https://info.holmusk.com/blog/capitalizing-on-untapped-value-extracting-environmental-stressors-from-clinical-notes-via-natural-language-processing) ![an illustration of books and a paper record beside a plant and a pair of glasses](https://info.holmusk.com/hubfs/MHM_blog%203.png) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [outcomes,](https://info.holmusk.com/blog/tag/outcomes) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [scales,](https://info.holmusk.com/blog/tag/scales) [environment,](https://info.holmusk.com/blog/tag/environment) [socioenvironmental factors,](https://info.holmusk.com/blog/tag/socioenvironmental-factors) [behavioral health assessments,](https://info.holmusk.com/blog/tag/behavioral-health-assessments) [structured data](https://info.holmusk.com/blog/tag/structured-data) ### [A look inside NeuroBlu: Structured socioenvironmental stressor data](https://info.holmusk.com/blog/a-look-inside-neuroblu-structured-socioenvironmental-stressor-data) May 15, 2023 7:30:00 AM Huge amounts of data are collected throughout a person’s journey through the behavioral healthcare system. From demographic data captured during intake to in-depth conversations between patients and clinicians about symptoms, daily activities, and goals, most of the information captured about a patient becomes part of their electronic health record (EHR).  ![Melissa Unruh](https://info.holmusk.com/hs-fs/hubfs/Untitled%20design%20(7).png?width=45&name=Untitled%20design%20(7).png) [Melissa Unruh](https://info.holmusk.com/blog/author/melissa-unruh) [Read More](https://info.holmusk.com/blog/a-look-inside-neuroblu-structured-socioenvironmental-stressor-data) ![](https://info.holmusk.com/hubfs/Copy%20of%20January%202023%20.png) [mental health,](https://info.holmusk.com/blog/tag/mental-health) [real-world data,](https://info.holmusk.com/blog/tag/real-world-data) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [public health,](https://info.holmusk.com/blog/tag/public-health) [environment,](https://info.holmusk.com/blog/tag/environment) [socioenvironmental factors](https://info.holmusk.com/blog/tag/socioenvironmental-factors) ### [Nature and nurture: How environment and biology shape mental health](https://info.holmusk.com/blog/nature-and-nurture-how-environment-and-biology-shape-mental-health) May 1, 2023 8:00:00 AM As a mental health clinician and researcher, I have seen firsthand how our understanding of the role that biological and socioenvironmental factors play in mental health has evolved over time. For many years, the debate over nature vs. nurture dominated discussions in the field, but more recent models have focused on the interaction between genes and the environment, such as the [diathesis stress model](https://dictionary.apa.org/diathesis-stress-model). ![Alex Vance](https://info.holmusk.com/hs-fs/hubfs/Alex%20Vance.jpeg?width=45&name=Alex%20Vance.jpeg) [Alex Vance](https://info.holmusk.com/blog/author/alex-vance) [Read More](https://info.holmusk.com/blog/nature-and-nurture-how-environment-and-biology-shape-mental-health) ![](https://info.holmusk.com/hubfs/hospital-g23a1d6cc3_1920.jpg) [RWD,](https://info.holmusk.com/blog/tag/rwd) [behavioral health,](https://info.holmusk.com/blog/tag/behavioral-health) [data capture,](https://info.holmusk.com/blog/tag/data-capture) [NeuroBlu Database,](https://info.holmusk.com/blog/tag/neuroblu-database) [scales,](https://info.holmusk.com/blog/tag/scales) [disease severity,](https://info.holmusk.com/blog/tag/disease-severity) [electronic health record,](https://info.holmusk.com/blog/tag/electronic-health-record) [hospitalization risk](https://info.holmusk.com/blog/tag/hospitalization-risk) ### [The value of NeuroBlu Data: Reflections on our study in The Lancet Psychiatry](https://info.holmusk.com/blog/the-value-of-neuroblu-data-reflections-on-our-study-in-the-lancet-psychiatry) Apr 20, 2023 10:49:13 AM I recently led a team of researchers in a large-scale observational study, which was accepted and published by [*The Lancet Psychiatry*](https://doi.org/10.1016/S2215-0366(23)00066-4). To our knowledge, our study was the first to study the impact of early clinical trajectory across multiple psychiatric diagnoses. ![Max Taquet](https://info.holmusk.com/hs-fs/hubfs/MaximeTaquet_photo.jpg?width=45&name=MaximeTaquet_photo.jpg) [Max Taquet](https://info.holmusk.com/blog/author/max-taquet) [Read More](https://info.holmusk.com/blog/the-value-of-neuroblu-data-reflections-on-our-study-in-the-lancet-psychiatry) [1](https://info.holmusk.com/blog/tag/behavioral-health) [2](https://info.holmusk.com/blog/tag/behavioral-health/page/2) #### Stay Connected with Us [Follow us on LinkedIn](https://www.linkedin.com/company/holmusk/) [Follow us on Twitter](https://twitter.com/holmusk) - [Recent News](https://www.holmusk.com/news) - [Latest Publications](https://www.holmusk.com/publications) - [Digital Solutions](https://www.holmusk.com/solutions)